1: With N-Acetyl-Dl-leucine in tetrahydrofuran; methanol T=15 - 55°C; 3.5 h; 2: With sodium hydroxide in water 1.5 h; Product distribution / selectivity;

1: With (+)-10-camphorsulfonic acid in ethanol Heating; 2: With potassium hydroxide 0.25 h; Heating; Further stages.;

2-(2,4,6-trimethyl-phenyl)-2,5,6,7-tetrahydro-pyrrolo[2,1-c] [1,2,4]triazol-4-ylium perchlorate; (4aR,9aS)-6-bromo-4-hydroxy-4,4a,9,9a-tetrahydroindeno[2,1-b][1,4]oxazin-3(2H)-one; potassium carbonate in isopropanol acetate T=23°C; 24 h; Resolution of racemate;

1: Jones reagent 2: 80 percent / 4-dimethylaminopyridine, 1,3-dicyclocyclohexylcarbodiimide / diethyl ether / Ambient temperature View Scheme

1: Jones reagent 2: 86 percent / NaOH / H2O; 2-methyl-propan-2-ol / 16 h / Ambient temperature View Scheme

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