5-乙基-3-苯基-1,2,4-恶二唑合成路线 （共 14 条）
反应条件
sulfuric acid; nitric acid T=-5 - 0°C;
参考文献
Palazzo,G.; Corsi,G.
Gazzetta Chimica Italiana, 1963 , vol. 93, p. 1196 - 1205
反应条件
in neat (no solvent)
T=80°C; 0.0833333 h; Green chemistry;
参考文献
Tadikonda, Ramu; Nakka, Mangarao; Gajula, Mahaboob Basha; Rayavarapu, Srinuvasarao; Gollamudi, Padma Rao; Vidavalur, Siddaiah
Synthetic Communications, 2014 , vol. 44, # 13 p. 1978 - 1986
反应条件
in neat (no solvent)
T=80°C; 0.116667 h; Green chemistry;
参考文献
Tadikonda, Ramu; Nakka, Mangarao; Gajula, Mahaboob Basha; Rayavarapu, Srinuvasarao; Gollamudi, Padma Rao; Vidavalur, Siddaiah
Synthetic Communications, 2014 , vol. 44, # 13 p. 1978 - 1986
反应条件
toluene-4-sulfonic acid
T=80°C; 0.15 h; Green chemistry;
参考文献
Mangarao, Nakka; Mahaboob Basha, Gajula; Ramu, Tadikonda; Srinuvasarao, Rayavarapu; Prasanthi, Sarakula; Siddaiah, Vidavalur
Tetrahedron Letters, 2014 , vol. 55, # 1 p. 177 - 179
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in toluene
T=90°C; 16 h;
参考文献
Steglich, Wolfgang; Ree, Teunis van
Synthetic Communications, 1982 , vol. 12, # 6 p. 457 - 462
反应条件
1: NH2OH; AcOH / 0.02 h / 100 °C / microwave irradiation
2: 0.03 h / 150 °C / microwave irradiation
View Scheme
参考文献
Adib, Mehdi; Mahdavi, Mohammad; Mahmoodi, Niusha; Pirelahi, Hooshang; Bijanzadeh, Hamid Reza
Synlett, 2006 , # 11 p. 1765 - 1767
反应条件
boron trifluoride diethyl etherate in diethyl ether
参考文献
Morrocchi,S. et al.
Tetrahedron Letters, 1967 , p. 331 - 334
反应条件
1-nitroethane; ammonium propionate
72 h; Heating;
参考文献
Young, Thomas E.; Beidler, William Thomas
Journal of Organic Chemistry, 1985 , vol. 50, # 8 p. 1182 - 1186
反应条件
1: 0.47 g / sodium carbonate, magnesium sulphate / diethyl ether / 2 h / Ambient temperature
2: 150 °C
View Scheme
参考文献
Ooi, Ngan Sim; Wilson, David A.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1792 - 1799
反应条件
1: 74 percent / CHCl3 / 2 h / Ambient temperature
2: 0.47 g / sodium carbonate, magnesium sulphate / diethyl ether / 2 h / Ambient temperature
3: 150 °C
View Scheme
参考文献
Ooi, Ngan Sim; Wilson, David A.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1792 - 1799
