(R)-(-)-2-羟丙基对甲苯磺酸盐合成路线 （共 7 条）
反应条件
1: With dimethyl amine; triethylamine in dichloromethane T=5°C; 2 h; 2: in dichloromethane T=20°C; 12 h;
参考文献
MERCK SHARP and DOHME LIMITED
Patent: WO2004/31191 A1, 2004 ;
Location in patent: Page 38 ;
WO 2004/031191 A1
反应条件
Fe(3+)-exchanged montmorillonite clay in 1,2-dichloro-ethane T=80°C; 4 h;
参考文献
Choudary, Boyapati M.; Chowdari, Naidu S.; Kantam, Mannepalli L.
Tetrahedron, 2000 , vol. 56, # 37 p. 7291 - 7298
反应条件
pyridine in dichloromethane; water
参考文献
Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
Patent: US4745066 A1, 1988 ;
反应条件
trifluoroacetic acid in dichloromethane T=25°C; 3 h; Title compound not separated from byproducts;
参考文献
Zefirov, N. S.; Kirin, V. N.; Yur'eva, N. M.; Zhdankin, V. V.; Kozmin, A. S.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 7 p. 1264 - 1279
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 7 p. 1402 - 1419
反应条件
di(n-butyl)tin oxide; triethylamine in dichloromethane T=20°C; Inert atmosphere; regioselective reaction;
参考文献
Shimada, Yasutaka; Usuda, Kazumasa; Okabe, Hirokazu; Suzuki, Tsuguru; Matsumoto, Kazutsugu
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2802 - 2808
参考文献
Green; Renfrew; Butler
Journal of the American Chemical Society, 1939 , vol. 61, p. 1783
参考文献
Wang, Fei; Wang, Shao Hua; Tu, Yong Qiang; Ren, Shi Kuo
Tetrahedron Asymmetry, 2003 , vol. 14, # 15 p. 2189 - 2193
