4,5-二乙氧基-2-硝基苯甲酸合成路线 （共 13 条）
反应条件
hydrogen; palladium on activated carbon in methanol
参考文献
Rexahan Corporation
Patent: US2005/187231 A1, 2005 ;
Location in patent: Page/Page column 18-19 ;
反应条件
1: 44 percent / SnCl2; aq. HCl / 2 h / 20 °C 2: 57 percent / 80 - 200 °C View Scheme
参考文献
VanBrocklin, Henry F.; Lim, John K.; Coffing, Stephanie L.; Hom, Darren L.; Negash, Kitaw; Ono, Michele Y.; Gilmore, Jennifer L.; Bryant, Ianthe; Riese II, David J.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7445 - 7456
反应条件
1: 44 percent / SnCl2; aq. HCl / 2 h / 20 °C 2: 57 percent / 80 - 200 °C 3: 73 percent / oxalyl chloride; DMF / 1,2-dichloro-ethane / 2.5 h / Heating View Scheme
参考文献
VanBrocklin, Henry F.; Lim, John K.; Coffing, Stephanie L.; Hom, Darren L.; Negash, Kitaw; Ono, Michele Y.; Gilmore, Jennifer L.; Bryant, Ianthe; Riese II, David J.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7445 - 7456
