1: 45 percent / TiCl4 / CH2Cl2 / -80 °C 2: 1.) CF3COOH, 2.) LiOH / 1.) room temp., 1.5 h., 2.) methanol-water, room temp. 3: 89 percent / H2 / PtO2 View Scheme

Multi-step reaction with 2 steps 1: 45 percent / TiCl4 / CH2Cl2 / -80 °C2: 1.) CF3COOH, 2.) LiOH / 1.) room temp., 1.5 h., 2.) methanol-water, room temp.