sodium hydroxide in 1,4-dioxane; water T=20°C; 6 h;

1: ethyl 2-[(4-cyanobenzyl)amino]-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-7-carboxylate With hydrogenchloride in 1,4-dioxane; water Reflux; 2: di-tert-butyl dicarbonate With sodium hydrogencarbonate in 1,4-dioxane; water T=20°C;