8-羟基-4-苯基-2-3,4-二氢苯并吡喃酮合成路线 (共 4 条)
反应条件
aluminium trichloride in nitrobenzene T=70 - 75°C; 12 h;
参考文献
Balayan, R. S.; Akopyan, M. G.; Vartanyan, R. M.; Kaltrikyan, A. A.; Avakyan, O. M.; et al.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 8 p. 558 - 562
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 8 p. 956 - 960
参考文献
Kabi Pharmacia AB
Patent: EP325571 B1, 1991 ;
反应条件
PPA T=95 - 100°C; 2 h;
参考文献
Majumder; Chatterjee; Mukhoti
Journal of the Indian Chemical Society, 2001 , vol. 78, # 10-12 p. 743 - 755
反应条件
1: triethylamine / tetrahydrofuran / 0 - 20 °C 2: p-toluenesulfonic acid monohydrate / 4 h / 140 °C / Inert atmosphere; Sealed Tube; Neat (no solvent) View Scheme
参考文献
Jeon, Jae-Ho; Yang, Deok-Mo; Jun, Jong-Gab
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 1 p. 65 - 70