苯并[d]噻唑-7-羧酸甲酯合成路线 （共 2 条）
反应条件
isopentyl nitrite in tetrahydrofuran 4 h; Heating / reflux;
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2009/104155 A1, 2009 ;
Location in patent: Page/Page column 58 ;
WO 2009/104155 A1
反应条件
1: With sodium hydroxide; water in tetrahydrofuran; methanol T=0°C; 4 h; 2: With hydrogenchloride in water T=0°C; pH=5; 0.5 h;
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2009/104155 A1, 2009 ;
Location in patent: Page/Page column 58-59 ;
WO 2009/104155 A1
