2-(二乙氧基甲基)苯甲醛合成路线 （共 4 条）
反应条件
1: 2-bromobenzaldehyde diethyl acetal With n-butyllithium in tetrahydrofuran; hexane T=-70°C; 0.5 h; Inert atmosphere; 2: N,N-dimethyl-formamide T=-70 - 20°C;
参考文献
Ueda, Masafumi; Kawai, Sayuri; Hayashi, Masataka; Naito, Takeaki; Miyata, Okiko
Journal of Organic Chemistry, 2010 , vol. 75, # 3 p. 914 - 921
反应条件
n-butyllithium in N-methyl-acetamide; diethyl ether; water
参考文献
Akzo Nobel, N.V.
Patent: US6080773 A1, 2000 ;
反应条件
ethanol; ammonium chloride
参考文献
Powell; Rexford
Journal of Organic Chemistry, 1953 , vol. 18, p. 810,811
反应条件
1: 67 percent / EtONa / ethanol / 4 h / 20 °C
2: 81 percent / concn. HCl / acetonitrile; H2O / 20 °C
View Scheme
参考文献
Chezal, Jean M.; Moreau, Emmanuel; Desbois, Nicolas; Blache, Yves; Chavignon, Olivier; Teulade, Jean C.
Tetrahedron Letters, 2004 , vol. 45, # 3 p. 553 - 556
