4-甲基-3-硝基苯甲酰氯合成路线 （共 16 条）
参考文献
Desrousseaux; Bennetau; Morand; Mingotaud; Letard; Montant; Freysz
New Journal of Chemistry, 2000 , vol. 24, # 12 p. 977 - 985
反应条件
1: triethylamine / dichloromethane / 20 °C
2: palladium 10 on activated carbon; hydrogen / ethanol / 20 °C
View Scheme
参考文献
Brown, Dearg S.; Cumming, John G.; Bethel, Paul; Finlayson, Jonathan; Gerhardt, Stefan; Nash, Ian; Pauptit, Richard A.; Pike, Kurt G.; Reid, Alan; Snelson, Wendy; Swallow, Steve; Thompson, Caroline
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 3879 - 3883
反应条件
1: With triethylamine in 1,2-dichloro-ethane
T=20°C; 2.5 h;
2: With citric acid in DCE; water
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2005/42537 A1, 2005 ;
Location in patent: Page/Page column 82; 83 ;
WO 2005/042537 A1
反应条件
1: 95 percent / 8 h / Heating
2: 60 percent / N-bromosuccinimide; benzoyl peroxide / CCl4 / 15 h / Heating
View Scheme
参考文献
Desrousseaux; Bennetau; Morand; Mingotaud; Letard; Montant; Freysz
New Journal of Chemistry, 2000 , vol. 24, # 12 p. 977 - 985
反应条件
1: triethylamine / dichloromethane / 20 °C
2: palladium 10 on activated carbon; hydrogen / ethanol / 20 °C
View Scheme
参考文献
Brown, Dearg S.; Cumming, John G.; Bethel, Paul; Finlayson, Jonathan; Gerhardt, Stefan; Nash, Ian; Pauptit, Richard A.; Pike, Kurt G.; Reid, Alan; Snelson, Wendy; Swallow, Steve; Thompson, Caroline
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 3879 - 3883
反应条件
1: triethylamine / dichloromethane / 20 °C
2: palladium 10 on activated carbon; hydrogen / ethanol / 20 °C
View Scheme
参考文献
Brown, Dearg S.; Cumming, John G.; Bethel, Paul; Finlayson, Jonathan; Gerhardt, Stefan; Nash, Ian; Pauptit, Richard A.; Pike, Kurt G.; Reid, Alan; Snelson, Wendy; Swallow, Steve; Thompson, Caroline
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 3879 - 3883
