6-甲氧基吲哚-3-乙酸合成路线 （共 16 条）
反应条件
potassium hydroxide in tetrahydrofuran; water T=20°C;
参考文献
Phytochemistry, , vol. 68, # 12 p. 1651 - 1663
反应条件
potassium hydroxide in ethanol 36 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 54, # 25 p. 5985 - 5988
反应条件
1: tetrahydrofuran / 2 h / 0 °C 2: triethylamine / tetrahydrofuran / 4 h / 20 °C 3: 74 percent / NaH2PO2*H2O / palladium on activated charcoal / dioxane; H2O / 48 h / 20 °C 4: 100 percent / KOH / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Phytochemistry, , vol. 68, # 12 p. 1651 - 1663
反应条件
1: triethylamine / tetrahydrofuran / 4 h / 20 °C 2: 74 percent / NaH2PO2*H2O / palladium on activated charcoal / dioxane; H2O / 48 h / 20 °C 3: 100 percent / KOH / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Phytochemistry, , vol. 68, # 12 p. 1651 - 1663
反应条件
1: 74 percent / NaH2PO2*H2O / palladium on activated charcoal / dioxane; H2O / 48 h / 20 °C 2: 100 percent / KOH / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Phytochemistry, , vol. 68, # 12 p. 1651 - 1663
反应条件
1: Zn, NH4Cl / ethanol; H2O 2: K2CO3 / diethyl ether; H2O / 1 h / 0 °C 3: 66 percent / N-methylmorpholine / CH2Cl2 / 1) r.t to 40 deg C 2) 1 h 4: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 5: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 6: ethanol / 2 h / Heating 7: KOH / ethanol; H2O / 10 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: K2CO3 / diethyl ether; H2O / 1 h / 0 °C 2: 66 percent / N-methylmorpholine / CH2Cl2 / 1) r.t to 40 deg C 2) 1 h 3: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 4: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 5: ethanol / 2 h / Heating 6: KOH / ethanol; H2O / 10 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: 66 percent / N-methylmorpholine / CH2Cl2 / 1) r.t to 40 deg C 2) 1 h 2: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 3: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 4: ethanol / 2 h / Heating 5: KOH / ethanol; H2O / 10 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 2: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 3: ethanol / 2 h / Heating 4: KOH / ethanol; H2O / 10 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: benzene 2: 82.9 percent / aq. ethanol / 24 h / Heating 3: 98.1 percent / KOH / aq. ethanol / 36 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 25 p. 5985 - 5988
