N-(3,4-二氢-4-氧代-2H-1-苯并噻喃-6-基)乙酰胺合成路线 （共 6 条）
反应条件
triethylamine in dichloromethane 0.5 h; Inert atmosphere;
参考文献
Song, Jiangli; Jones, Lindsay M.; Kumar, G. D. Kishore; Conner, Elizabeth S.; Bayeh, Liela; Chavarria, Gustavo E.; Charlton-Sevcik, Amanda K.; Chen, Shen-En; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 450 - 453
反应条件
1: aqueous hydrochloric acid; tin View Scheme
参考文献
Song, Jiangli; Jones, Lindsay M.; Kumar, G. D. Kishore; Conner, Elizabeth S.; Bayeh, Liela; Chavarria, Gustavo E.; Charlton-Sevcik, Amanda K.; Chen, Shen-En; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 450 - 453
反应条件
1.1: sodium hydroxide / water / Cooling with ice 1.2: Cooling with ice; Reflux 2.1: polyphosphoric acid / 1 h / 60 °C 3.1: hydrogenchloride; tin / tetrahydrofuran; water / 4 h / Inert atmosphere 4.1: triethylamine / dichloromethane / 0.5 h / Inert atmosphere View Scheme
参考文献
Song, Jiangli; Jones, Lindsay M.; Kumar, G. D. Kishore; Conner, Elizabeth S.; Bayeh, Liela; Chavarria, Gustavo E.; Charlton-Sevcik, Amanda K.; Chen, Shen-En; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 450 - 453
反应条件
1: SOCl2 2: AlCl3 View Scheme
参考文献
Katsura; Tomishi; Inoue; Sakane; Matsumoto; Morinaga; Ishikawa; Takasugi
Journal of Medicinal Chemistry, 2000 , vol. 43, # 17 p. 3315 - 3321
反应条件
2: SOCl2 3: AlCl3 View Scheme
参考文献
Katsura; Tomishi; Inoue; Sakane; Matsumoto; Morinaga; Ishikawa; Takasugi
Journal of Medicinal Chemistry, 2000 , vol. 43, # 17 p. 3315 - 3321
反应条件
1: alkaline water 2: phosphorus (V)-oxide; concentrated sulfuric acid 3: aqueous hydrochloric acid; tin View Scheme
参考文献
Bellavita
Gazzetta Chimica Italiana, 1940 , vol. 70, p. 584,592
