反应条件
1: 2,4-dichloro-1H-pyrrololt;2,3-dgt;pyrimidine With sodium hydride in tetrahydrofuran T=0 - 20°C; 2: toluene-4-sulfonic acid in tetrahydrofuran T=20°C; 18 h;
参考文献
PALAU PHARMA, S.A.; SALAS SOLANA, Jorge; ALMANSA ROSALES, Carmen; SOLIVA SOLIVA, Robert; FONTES USTRELL, Montserrat; COMELLES ESPUGA, Josep
Patent: WO2010/34740 A1, 2010 ;
Location in patent: Page/Page column 67 ;
WO 2010/034740 A1