反应条件
1.1: N-bromosuccinmide; dibenzoyl peroxide / chlorobenzene / 4 h / 85 °C
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C / |Inert atmosphere; |Sonication
2.2: 12 h / 20 °C / |Inert atmosphere
3.1: tetra-(n-butyl)ammonium iodide; potassium carbonate / 24 h / 80 °C / |Sealed tube
View Scheme
参考文献
Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda Gronborg; Koldso, Heidi; Schiott, Birgit; Stromgaard, Kristian; Kristensen, Anders S.
Molecular Pharmacology, 2014 , vol. 85, # 5 p. 703 - 714