反应条件
1: 1.) n-butyl-lithium / 1.) ether, 4 h, -15 deg C, 2.) 2 h, -15 deg C
2: 69.3 percent / glacial acetic acid, 20percent H2SO4 / H2O / 2 h / 120 °C
3: 82.3 percent / boron trifluoride etherate / CH2Cl2 / 2 h / Ambient temperature
4: 1.) sodium hydride / 1,2-dimethoxy-ethane / 1.) 0.5 h, 70 deg, 2.) 1 h, reflux
5: 79.5 percent / sodium borohydride / methanol / 1 h / Ambient temperature
6: 44.3 percent / pyridine / 8 h / Ambient temperature
7: 33.6 percent / lithium bromide / dimethylformamide / 5 h / 80 °C
8: 78.7 percent / methyl iodide / H2O; acetone / 5 h / Heating
View Scheme
参考文献
Kametani, Tetsuji; Tsubuki, Masayoshi; Nemoto, Hideo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 759 - 761
