反应条件
1.1: N-bromosuccinmide / 0.25 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran / -40 - -20 °C / |Inert atmosphere
2.2: 3 h / -78 °C / |Inert atmosphere
3.1: 18-crown-6 ether / dimethyl sulfoxide / 4 h / 100 °C / |Inert atmosphere
4.1: iodine; sodium hydrogencarbonate; water / acetone / 2 h / 0 °C
View Scheme
参考文献
Franz, Sarah E.; Watkins, Richard R.; Wright, Laura A.; Weaver, Blair A.; Hartage, Ramon C.; Ghiviriga, Ion; Gumina, Giuseppe; Feske, Brent D.
Synthesis (Germany), 2013 , vol. 45, # 15 art. no. SS-2013-M0268-OP, p. 2171 - 2178
