1: 1-bromo-4-methoxy-benzene With potassium tert-butylate; thiourea in dimethyl sulfoxide 3 h; UV-irradiation; 2: methyl iodide in water; dimethyl sulfoxide Title compound not separated from byproducts;
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran Inert atmosphere; 2: 4-bromo-pyridine-hydrochloride With NiCl2((PPh3)P)2 in tetrahydrofuran T=10 - 50°C; Inert atmosphereCooling;
参考文献
Organic Process Research and Development, , vol. 7, # 3 p. 436 - 445
