trifluoroacetic acid in dichloromethane 1.5 h; Ambient temperature;
参考文献
Brown, Frederick J.; Bernstein, Peter R.; Cronk, Laura A.; Dosset, David L.; Hebbel, Kevin C.; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 4 p. 811 - 826
1: 92 percent / K2CO3 / acetone / 12 h / Heating 2: 82 percent / CF3CO2H / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Brown, Frederick J.; Bernstein, Peter R.; Cronk, Laura A.; Dosset, David L.; Hebbel, Kevin C.; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 4 p. 811 - 826
1: 78 percent / tetrahydrofuran / 5 h / Heating 2: 74 percent / CBr4, Ph3P / CH2Cl2 / 1.5 h / 0 °C 3: 92 percent / K2CO3 / acetone / 12 h / Heating 4: 82 percent / CF3CO2H / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Brown, Frederick J.; Bernstein, Peter R.; Cronk, Laura A.; Dosset, David L.; Hebbel, Kevin C.; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 4 p. 811 - 826
1: 74 percent / CBr4, Ph3P / CH2Cl2 / 1.5 h / 0 °C 2: 92 percent / K2CO3 / acetone / 12 h / Heating 3: 82 percent / CF3CO2H / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Brown, Frederick J.; Bernstein, Peter R.; Cronk, Laura A.; Dosset, David L.; Hebbel, Kevin C.; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 4 p. 811 - 826
