1.1: sodium iodate; sulfuric acid / 2 h / 110 °C 1.2: 70 percent / sodium iodide; copper(I) iodide / dimethylformamide / 5 h / 110 °C 2.1: 57 percent / pyridine / 8 h / 95 °C 3.1: 72 percent / tin(II) chloride dihydrate / ethanol; ethyl acetate / 4 h / 85 °C 4.1: sodium nitrite; hydrochloric acid / acetonitrile; H2O / 0.5 h / 0 °C 4.2: 14 percent / potassium iodide / acetonitrile; H2O / 18 h / 20 °C 5.1: 86 percent / n-butyllithium / tetrahydrofuran; hexane / -78 - -42 °C View Scheme

1.1: 57 percent / pyridine / 8 h / 95 °C 2.1: 72 percent / tin(II) chloride dihydrate / ethanol; ethyl acetate / 4 h / 85 °C 3.1: sodium nitrite; hydrochloric acid / acetonitrile; H2O / 0.5 h / 0 °C 3.2: 14 percent / potassium iodide / acetonitrile; H2O / 18 h / 20 °C 4.1: 86 percent / n-butyllithium / tetrahydrofuran; hexane / -78 - -42 °C View Scheme

platinum (IV)-chloride; Aliquatreg; 336 in water; 1,2-dichloro-ethane 24 h; Heating;