6-甲基-6-庚烯-2-酮合成路线 （共 52 条）
反应条件
lithium diisopropyl amide
1.) THF, -78 deg C, 45 min, 2.) THF, -78 deg C, 3 h; Multistep reaction;
参考文献
Perez; Gries; Oehlschlager
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 3 p. 445 - 450
反应条件
1: 97 percent / pyridine
2: 1.) sodium iodide, 2.) DBU / 1.) DMF, 50 deg C, 3.5 h, 2.) 80 deg C, 3.5 h
View Scheme
参考文献
Dhokte, U. P.; Rao, A. S.
Synthetic Communications, 1988 , vol. 18, # 8 p. 811 - 822
反应条件
1: aqueous sulfuric acid / anschliessendes Erwaermen mit Aethanol
2: bromoacetic acid ethyl ester / ueber mehrere Stufen
3: diethyl ether
View Scheme
参考文献
Kappeler et al.
Helvetica Chimica Acta, 1954 , vol. 37, p. 957,962
反应条件
1: bromoacetic acid ethyl ester / ueber mehrere Stufen
2: diethyl ether
View Scheme
参考文献
Kappeler et al.
Helvetica Chimica Acta, 1954 , vol. 37, p. 957,962
参考文献
Kappeler et al.
Helvetica Chimica Acta, 1954 , vol. 37, p. 957,962
参考文献
Turpin; Weigel
Tetrahedron Letters, 1992 , vol. 33, # 44 p. 6563 - 6564
反应条件
2: 220 °C
View Scheme
参考文献
Streinz, Ludvik; Wimmer, Zdenek; Roshka, Georgii K.; Ishchenko, Raisa I.; Romanuk, Miroslav; Kovalev, Boris G.
Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 10 p. 2174 - 2178
反应条件
(i) Mg, Et2O, (ii) /BRN= 385737/; Multistep reaction;
参考文献
Ansell,M.F.; Thomas,D.A.
Journal of the Chemical Society, 1961 , p. 539 - 542
反应条件
T=220°C; Yield given. Yields of byproduct given;
参考文献
Streinz, Ludvik; Wimmer, Zdenek; Roshka, Georgii K.; Ishchenko, Raisa I.; Romanuk, Miroslav; Kovalev, Boris G.
Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 10 p. 2174 - 2178
反应条件
1: (MeO)2P(O)CH2CO2Et With sodium hydride in tetrahydrofuran
2: 2-methyl-6-oxo-hept-1-ene in tetrahydrofuran
Horner-Wittig reaction;
参考文献
Singh, Vasundhara; Chaudhary, Sangeeta; Sapehiyia, Varinder; Kaur, Irvinder; Kad, Goverdhan Lal; Singh, Jasvinder
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 9 p. 1950 - 1953
