3,5-二碘-L-甲状腺素合成路线 （共 16 条）
反应条件
2: (-)-α-phenethylamine; water 3: hydrobromic acid View Scheme
参考文献
Biochemical Journal, , vol. 22, p. 1433
反应条件
iodine; methylamine; potassium iodide in water T=0 - 5°C; 2 h;
参考文献
CADILA PHARMACEUTICALS LTD.
Patent: WO2009/136249 A1, 2009 ;
Location in patent: Page/Page column 4 ;
参考文献
Taurog et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 3473,3476
参考文献
Dibra S.p.A.
Patent: US6337064 B1, 2002 ;
Location in patent: Page column 33 ;
反应条件
potassium hydroxide; palladium Hydrogenation;
参考文献
Canzanelli; Harington; Randall
Biochemical Journal, 1934 , vol. 28, p. 68,71
反应条件
sodium hydroxide; iodine
参考文献
Gross; Pitt-Rivers
Biochemical Journal, 1953 , vol. 53, p. 645,647
