2’-氨基-2’-脱氧腺苷合成路线 （共 13 条）
反应条件
1: 93 percent / pyridine / Ambient temperature 2: 94 percent / Bu3SnH, AIBN / toluene / 2.5 h / 115 °C 3: TBAF / tetrahydrofuran View Scheme
参考文献
Journal of the American Chemical Society, , vol. 118, # 46 p. 11341 - 11348
反应条件
1: 94 percent / Bu3SnH, AIBN / toluene / 2.5 h / 115 °C 2: TBAF / tetrahydrofuran View Scheme
参考文献
Journal of the American Chemical Society, , vol. 118, # 46 p. 11341 - 11348
反应条件
in water T=63°C; 15 h; in the presence of Enterobacter aerogenes, and KH2PO4;
参考文献
Agricultural and Biological Chemistry, , vol. 49, # 9 p. 2711 - 2718
反应条件
1.1: DMAP / CH2Cl2 / 3 h / 0 °C 2.1: DBU / acetonitrile 3.1: pyridine 3.2: morpholine 4.1: 95 percent / Et3N*HF / tetrahydrofuran 5.1: 40 percent aq. CH3NH2 View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 22 p. 3345 - 3347
反应条件
1.1: DBU / acetonitrile 2.1: pyridine 2.2: morpholine 3.1: 95 percent / Et3N*HF / tetrahydrofuran 4.1: 40 percent aq. CH3NH2 View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 22 p. 3345 - 3347
反应条件
1.1: pyridine 2.1: DMAP / CH2Cl2 / 3 h / 0 °C 3.1: DBU / acetonitrile 4.1: pyridine 4.2: morpholine 5.1: 95 percent / Et3N*HF / tetrahydrofuran 6.1: 40 percent aq. CH3NH2 View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 22 p. 3345 - 3347
反应条件
1.1: pyridine 1.2: morpholine 2.1: 95 percent / Et3N*HF / tetrahydrofuran 3.1: 40 percent aq. CH3NH2 View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 22 p. 3345 - 3347
反应条件
1: 95 percent / Et3N*HF / tetrahydrofuran 2: 40 percent aq. CH3NH2 View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 22 p. 3345 - 3347
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 22 p. 3345 - 3347
反应条件
ammonia; sodium methylate 1.) methanol, 120 deg C, 3 h, autoclave, 2.) methanol, reflux, 8 h; Yield given. Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 11 p. 3191 - 3195
