(9CI)-吡啶并[2,3-e]吡咯并[1,2-a]吡嗪-6(4H)-酮合成路线 （共 17 条）
反应条件
1: acetic acid / Heating
2: 83 percent / POCl3 / 60 deg C, 15 min, 100 deg C, 1 h
3: 51 percent / NaOH (15percent), Ag2O / 4 h / Heating
4: 54 percent / 0.08 h / 180 °C
5: 81 percent / 1 h / 90 °C / Heating
View Scheme
参考文献
Lancelot; Laduree; Robba
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3122 - 3128
反应条件
1: 83 percent / POCl3 / 60 deg C, 15 min, 100 deg C, 1 h
2: 51 percent / NaOH (15percent), Ag2O / 4 h / Heating
3: 54 percent / 0.08 h / 180 °C
4: 81 percent / 1 h / 90 °C / Heating
View Scheme
参考文献
Lancelot; Laduree; Robba
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3122 - 3128
反应条件
1: 71 percent / hydrazine hydrate / ethanol / 4 h / Heating
2: 63 percent / NaN3 / aq. acetic acid / 1 h / Ambient temperature
3: 66 percent / 3 h / Heating
4: 69 percent / toluene / 1.5 h / Heating
View Scheme
参考文献
Lancelot; Laduree; Robba
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3122 - 3128
反应条件
1: 48 percent / acetic acid / 1 h / Heating
2: 63 percent / ammonia / methanol / 23 h / 260 °C
3: 1 h / Heating
View Scheme
参考文献
Peet, Norton P.; Sunder, Shyam
Heterocycles, 1986 , vol. 24, # 11 p. 3213 - 3221
反应条件
1: 40 percent / acetic acid / Heating
2: 63 percent / toluene / 1 h / Heating
3: 81 percent / 1 h / 90 °C / Heating
View Scheme
参考文献
Lancelot; Laduree; Robba
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3122 - 3128
反应条件
1: 63 percent / toluene / 1 h / Heating
2: 81 percent / 1 h / 90 °C / Heating
View Scheme
参考文献
Lancelot; Laduree; Robba
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3122 - 3128
参考文献
Peet, Norton P.; Sunder, Shyam
Heterocycles, 1986 , vol. 24, # 11 p. 3213 - 3221
