1: 93 percent / pyridine / 40 h / Ambient temperature 2: 97 percent / aq. AcOH / tetrahydrofuran / 40 h / Ambient temperature 3: 80 percent / CdCO3 / toluene / 2.5 h / Heating 4: 65 percent / aq. NaOH / methanol / 24 h / Ambient temperature View Scheme

Multi-step reaction with 4 steps 1: 87 percent / pyridine / 0.5 h / 0 °C2: 69 percent / CdCO3 / toluene / Heating3: 78 percent / aq. AcOH / tetrahydrofuran / Ambient temperature4: 65 percent / aq. NaOH / methanol / 24 h / Ambient temperature  

With  acetic anhydride in  pyridine Show Experimental Procedure  

Multi-step reaction with 2 steps 1: 93 percent / pyridine / 40 h / Ambient temperature2: 97 percent / aq. AcOH / tetrahydrofuran / 40 h / Ambient temperature  

 in  pyridine; propionic acid anhydride Show Experimental Procedure