(2,5-二氧代吡咯烷-1-基)(4R)-4-[(3R,5R,10S,13R,17S)-3-羟基-10,13-二甲基-2,3,4,5,6,7,8,9,11,12,14,15,16,17-十四氢-1H-环戊二烯并[a]菲-17-基]戊酸酯合成路线 （共 2 条）
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104211-94-1(2,5-二氧代吡咯烷-1-基)(4R)-4-[(3R,5R,10S,13R,17S)-3-羟基-10,13-二甲基-2,3,4,5,6,7,8,9,11,12,14,15,16,17-十四氢-1H-环戊二烯并[a]菲-17-基]戊酸酯
反应条件
N-ethyl-N,N-diisopropylamine in DMF (N,N-dimethyl-formamide) T=20°C; 2 h;
参考文献
Mahato, Ram I.; Maheshwari, Anurag; Kim, Sung Wan
Patent: US2005/32722 A1, 2005 ;
Location in patent: Page/Page column 4 ;
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104211-94-1(2,5-二氧代吡咯烷-1-基)(4R)-4-[(3R,5R,10S,13R,17S)-3-羟基-10,13-二甲基-2,3,4,5,6,7,8,9,11,12,14,15,16,17-十四氢-1H-环戊二烯并[a]菲-17-基]戊酸酯
反应条件
dicyclohexyl-carbodiimide in tetrahydrofuran 3.5 h;
参考文献
NAH, Jae-Woon; JUNG, Teok Rae
Patent: WO2007/86651 A1, 2007 ;
Location in patent: Page/Page column 25-26 ;
