反应条件
1.1: 83 percent / Dowex 50WX8-H(1+) resin / ethanol / 2 h / Heating 2.1: 99 percent / NEt3 / CH2Cl2 / 3 h / 0 - 20 °C 3.1: 47 percent / HCl / H2O; dioxane / 18 h / 20 °C 4.1: 95 percent / NEt3; DMAP; 3 Angstroem molecular sieves / acetonitrile / 1 h / 20 °C 5.1: bis(trimethylsilyl)acetamide / dimethylformamide / 1.5 h / 20 °C 5.2: 81 percent / TMSOTf / dimethylformamide / 3 h / 0 - 5 °C 6.1: 42 percent / aq. NaOH / dioxane / 4 h / 20 °C 7.1: DIBAL-H / tetrahydrofuran / 24 h / 20 °C 8.1: NEt3; DMAP / CH2Cl2 / 2 h / Heating 9.1: 81 percent / hydrogen; NEt3 / Pd/C / ethyl acetate / 4 h / 50 °C / 760 Torr View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 9 p. 1781 - 1784
