zinc in acetic acid 0.25 h; Heating;

1: 70 percent / methanol / 48 h / Ambient temperature 2: 63 percent / Zn / acetic acid / 0.25 h / Heating View Scheme

1.1: bromo-dimethylsulfonium bromide / dichloromethane / 1 h / 20 °C / |Inert atmosphere 1.2: -78 - 20 °C / |Inert atmosphere 2.1: acetic acid; iron / ethanol / 0.08 h / 20 °C / |Reflux 3.1: potassium carbonate; 1,4-diaza-bicyclo[2.2.2]octane; copper(l) iodide / 1,4-dioxane / 12 h / |Schlenk technique; |Inert atmosphere; |Reflux View Scheme

1: With methanol; sodium hydroxide; water T=20°C; 16 h; 2: With hydrogenchloride in water pH=3 - 4;