O3-[2-[4-[二(苯基)甲基]哌嗪-1-基]乙基]O5-甲基2,6-二甲基-4-(3-硝基苯基)吡啶-3,5-二羧酸酯合成路线 （共 4 条）
反应条件
nitric acid in 1,4-dioxane T=70°C; 1.5 h;
参考文献
Meguro; Aizawa; Sohda; Kawamatsu; Nagaoka
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3787 - 3797
反应条件
1: 739.8 g / 2 h / 70 - 80 °C 2: 20 percent NH3/EtOH 3: 17.8 percent / propan-2-ol / 6 h / Heating 4: 90.1 percent / 2 N HNO3 / dioxane / 1.5 h / 70 °C View Scheme
参考文献
Meguro; Aizawa; Sohda; Kawamatsu; Nagaoka
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3787 - 3797
反应条件
1: 20 percent NH3/EtOH 2: 17.8 percent / propan-2-ol / 6 h / Heating 3: 90.1 percent / 2 N HNO3 / dioxane / 1.5 h / 70 °C View Scheme
参考文献
Meguro; Aizawa; Sohda; Kawamatsu; Nagaoka
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3787 - 3797
反应条件
1: 17.8 percent / propan-2-ol / 6 h / Heating 2: 90.1 percent / 2 N HNO3 / dioxane / 1.5 h / 70 °C View Scheme
参考文献
Meguro; Aizawa; Sohda; Kawamatsu; Nagaoka
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3787 - 3797
