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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
104450-90-0
合成路线
(共 6 条)
104450-90-0
→
反应条件
81024-42-2
美托洛尔
反应条件
1: 96 percent / conc. sulfuric acid / methanol / 96 h / Ambient temperature 2: 77 percent / Heating View Scheme
参考文献
Lamm, Bo; Ankner, Kjell; Frantsi, Marianne
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 3 p. 202 - 207
124-63-0
甲烷磺酰氯
+
104450-89-7
→
反应条件
104450-90-0
反应条件
With triethylamine in dichloromethane 0 deg C, 1 h -> room temperature, 1 h;
参考文献
Lamm, Bo; Ankner, Kjell; Frantsi, Marianne Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 3 p. 202 - 207
104450-87-5
→
反应条件
104450-90-0
反应条件
Multi-step reaction with 3 steps 1: 96 percent / lead tetraacetate / CH2Cl2 / 0 deg C, 1 h -> room temperature, 1 h2: ethyltributylammonium borohydride / CH2Cl2; 1,2-dichloro-ethane / Ambient temperature3: 87 percent / triethylamine / CH2Cl2 / 0 deg C, 1 h -> room temperature, 1 h
参考文献
Lamm, Bo; Ankner, Kjell; Frantsi, Marianne Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 3 p. 202 - 207
104450-88-6
→
反应条件
104450-90-0
反应条件
Multi-step reaction with 2 steps 1: ethyltributylammonium borohydride / CH2Cl2; 1,2-dichloro-ethane / Ambient temperature2: 87 percent / triethylamine / CH2Cl2 / 0 deg C, 1 h -> room temperature, 1 h
参考文献
Lamm, Bo; Ankner, Kjell; Frantsi, Marianne Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 3 p. 202 - 207
114218-32-5
→
反应条件
104450-90-0
反应条件
Multi-step reaction with 4 steps 1: 75 percent / aq. HCOOH2: 96 percent / lead tetraacetate / CH2Cl2 / 0 deg C, 1 h -> room temperature, 1 h3: ethyltributylammonium borohydride / CH2Cl2; 1,2-dichloro-ethane / Ambient temperature4: 87 percent / triethylamine / CH2Cl2 / 0 deg C, 1 h -> room temperature, 1 h
参考文献
Lamm, Bo; Ankner, Kjell; Frantsi, Marianne Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 3 p. 202 - 207
104450-90-0
→
反应条件
114218-34-7
反应条件
With sulfuric acid in methanol 96 h; Ambient temperature;
参考文献
Lamm, Bo; Ankner, Kjell; Frantsi, Marianne Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 3 p. 202 - 207