2-氨基-4,6-二氯吡啶-3-羧酸甲酯合成路线 （共 3 条）
反应条件
N-ethyl-N,N-diisopropylamine; trichlorophosphate T=20°C; 72 h;
参考文献
JAPAN TOBACCO INC.
Patent: US2011/77267 A1, 2011 ;
Location in patent: Page/Page column 48 ;
US 20110077267 A1
反应条件
1: With Ni(acac)2 in 1,4-dioxane 16 h; Reflux; 2: With trichlorophosphate 0.583333 h; Reflux;
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter Ronald
Patent: US2013/281397 A1, 2013 ;
Location in patent: Paragraph 0588; 0589 ;
反应条件
1: bis(acetylacetonate)nickel(II) / 1,4-dioxane / 16 h / Reflux 2: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 72 h / 20 °C View Scheme
参考文献
US2011/77267 A1, ;
US 20110077267 A1
