1: NaBH4 / methanol / 2 h / 0 °C 2: 1.4 g / Ph3P, diethyl azodicarboxylate / toluene / Ambient temperature 3: 650 mg / aq. K2CO3 / methanol / 1 h / Ambient temperature 4: 1.) B2H6, 2.) NaOH, aq. H2O2 / multistep reaction: 1.) THF, 0 deg C, 4 h, 2.) overnight; hydroboration of androst-4-enes; stereochemical aspects View Scheme
参考文献
Hanson, James R.; Hitchcock, Peter B.; Liman, Mansur D.; Naragatnam, Sivajini
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 17 p. 2183 - 2188
1: NaBH4 / methanol / 2 h / 0 °C 2: 1.4 g / Ph3P, diethyl azodicarboxylate / toluene / Ambient temperature 3: 650 mg / aq. K2CO3 / methanol / 1 h / Ambient temperature 4: 1.) B2H6, 2.) NaOH, aq. H2O2 / multistep reaction: 1.) THF, 0 deg C, 4 h, 2.) overnight; hydroboration of androst-4-enes; stereochemical aspects View Scheme
参考文献
Hanson, James R.; Hitchcock, Peter B.; Liman, Mansur D.; Naragatnam, Sivajini
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 17 p. 2183 - 2188