N-叔丁氧羰基-L-4-苯甲酰基苯丙氨酸合成路线 (共 6 条)
反应条件
sodium hydroxide in methanol T=20°C; Hydrolysis;
参考文献
Morera, Enrico; Ortar, Giorgio
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 16 p. 1815 - 1818
反应条件
hydrogen; triethylamine; palladium on activated charcoal in ethanol 1.5 h;
参考文献
Journal of Organic Chemistry, , vol. 60, # 7 p. 2292 - 2297
反应条件
1: 88 percent / PdCl2; PPh3 / dimethylformamide / 5 h / 90 °C 2: 100 percent / aq. NaOH / methanol / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 16 p. 1815 - 1818
反应条件
1: 88 percent / PdCl2; PPh3 / dimethylformamide / 5 h / 90 °C 2: 100 percent / aq. NaOH / methanol / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 16 p. 1815 - 1818
反应条件
1: 64 percent / PdCl2; PPh3; K2CO3 / dioxane / 18 h / 80 °C 2: 100 percent / aq. NaOH / methanol / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 16 p. 1815 - 1818
反应条件
4-methyl-morpholine in tetrahydrofuran; water; ethyl acetate; acetone
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4762881 A1, 1988 ;