尿苷酰基-(2'-5')-腺苷合成路线 (共 5 条)
反应条件
1.1: bis(2-pyridinyl)-disulfide; triethylamine; triphenylphosphine / dimethyl sulfoxide; N,N-dimethyl-formamide / 3 h
1.2: 2 h
2.1: Na(+)-montmorillonite / 1 h / 24 °C
2.2: 24 °C
View Scheme
参考文献
Joshi, Prakash C.; Aldersley, Michael F.; Zagorevskii, Dmitri V.; Ferris, James P.
Nucleosides, Nucleotides and Nucleic Acids, 2012 , vol. 31, # 7 p. 536 - 566
反应条件
1: 3N-(D-1-ribose)-uracil With Na(+)-montmorillonite
T=24°C; 1 h;
2: D-ImpA T=24°C;
参考文献
Joshi, Prakash C.; Aldersley, Michael F.; Zagorevskii, Dmitri V.; Ferris, James P.
Nucleosides, Nucleotides and Nucleic Acids, 2012 , vol. 31, # 7 p. 536 - 566
反应条件
1,4-dioxane; tributyl-amine; phenylphosphorochloridate
Erwaermen des Reaktionsprodukts mit wss.NH3;
参考文献
Michelson
Journal of the Chemical Society, 1959 , p. 3655,3664,3666
Biochemical Preparations, 1963 , vol. 10, p. 131
反应条件
1: With potassium chloride; magnesium chloride
T=37°C; pH=8; 17 h; aq. bufferEnzymatic reaction;
2: With shrimp alkaline phosphatase; magnesium chloride
T=37°C; pH=8; 1 h; aq. bufferEnzymatic reaction;
参考文献
Lopp, Annika; Reintamm, Tonu; Kuusksalu, Anne; Tammiste, Indrek; Pihlak, Arno; Kelve, Merike
Marine Drugs, 2010 , vol. 8, # 2 p. 235 - 254
反应条件
in water
T=90°C; Kinetics;
参考文献
Mikkola; Oivanen; Neuvonen; Piitari; Ketomaeki; Loennberg
Nucleosides, Nucleotides and Nucleic Acids, 2000 , vol. 19, # 10-12 p. 1675 - 1692