potassium tert-butylate in tert-butyl alcohol T=60°C; 2.5 h;

1H-imidazole in N,N-dimethyl-formamide 3.5 h; Ambient temperature;

1: 9.9 g / sodium periodate / methanol; H2O / 20 h / Ambient temperature 2: 87 percent / NaBH4 / ethanol / 2 h / Ambient temperature 3: 77 percent / pyridine / 24 h / Ambient temperature 4: 73 percent / 80percent acetic acid / 6 h / 65 °C 5: 93 percent / imidazole / dimethylformamide / 3.5 h / Ambient temperature View Scheme

1: 77 percent / pyridine / 24 h / Ambient temperature 2: 73 percent / 80percent acetic acid / 6 h / 65 °C 3: 93 percent / imidazole / dimethylformamide / 3.5 h / Ambient temperature View Scheme

1: 87 percent / NaBH4 / ethanol / 2 h / Ambient temperature 2: 77 percent / pyridine / 24 h / Ambient temperature 3: 73 percent / 80percent acetic acid / 6 h / 65 °C 4: 93 percent / imidazole / dimethylformamide / 3.5 h / Ambient temperature View Scheme

1: 73 percent / 80percent acetic acid / 6 h / 65 °C 2: 93 percent / imidazole / dimethylformamide / 3.5 h / Ambient temperature View Scheme

1: 59 percent / t-BuOK / 2-methyl-propan-2-ol / 2.5 h / 60 °C 2: 79 percent / tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / Ambient temperature View Scheme