4,7-二氢-7-氧代吡唑并[1,5-a]嘧啶-3-羧酸乙酯合成路线 (共 2 条)
反应条件
1: ethyl acetate; formic acid ethyl ester With sodium in ethanol; toluene T=20°C; 16 h; 2: 5-amino-1H-pyrazole-4-carboxylic acid ethyl ester in ethanol; toluene T=80°C; 4 h; Further stages.;
参考文献
Gavrin, Lori K.; Lee, Arthur; Provencher, Brian A.; Massefski, Walter W.; Huhn, Stephen D.; Ciszewski, Gregory M.; Cole, Derek C.; McKew, John C.
Journal of Organic Chemistry, 2007 , vol. 72, # 3 p. 1043 - 1046
反应条件
sodium ethanolate; acetic acid in ethanol T=85 - 90°C; 1 h;
参考文献
Chu; Suh; Mesbah; Cutler
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 2 p. 349 - 352