(S)-(-)-N-Z-吖丙啶-2-羧酸甲酯合成路线 （共 14 条）
反应条件
1: (S)-1-trityl-aziridine-2-carboxylic acid methyl ester With trifluoroacetic acid in methanol; chloroform T=0°C; 4 h; 2: benzyl chloroformate in water; ethyl acetate T=20°C; 20 h;
参考文献
Adams, Benjamin; Lowpetch, Kreingkrai; Thorndycroft, Faye; Whyte, Sheena M.; Young, Douglas W.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 18 p. 3357 - 3364
反应条件
triethylamine in chloroform T=20°C; 16 h;
参考文献
Belohradsky, Martin; Ridvan, Ludek; Zavada, Jiri
Collection of Czechoslovak Chemical Communications, 2003 , vol. 68, # 7 p. 1319 - 1325
反应条件
1: Boc-NHOTs; acrolein With (S)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; sodium acetate in chloroform T=20°C; 2: methanol With sodium cyanide; manganese(IV) oxide T=0°C; 0.666667 h; optical yield given as percent eeenantioselective reaction;
参考文献
Deiana, Luca; Dziedzic, Pawel; Zhao, Gui-Ling; Vesely, Jan; Ibrahem, Ismail; Rios, Ramon; Sun, Junliang; Cordova, Armando
Chemistry - A European Journal, 2011 , vol. 17, # 28 p. 7904 - 7917
反应条件
4-(N,N-dimethlyamino)pyridine T=20°C; 5 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 76, # 15 p. 6277 - 6285
反应条件
sodium hydrogencarbonate in diethyl ether; water T=0 - 10°C; 2 h; Yield given;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 21 p. 3219 - 3225
反应条件
indole; hafnium(IV) trifluoromethanesulfonate in dichloromethane T=20°C; 24 h;
参考文献
Tirotta, Ilaria; Fifer, Nathan L.; Eakins, Julia; Hutton, Craig A.
Tetrahedron Letters, 2013 , vol. 54, # 7 p. 618 - 620
反应条件
copper(II) bis(trifluoromethanesulfonate) in dichloromethane T=20°C; 24 h;
参考文献
Tirotta, Ilaria; Fifer, Nathan L.; Eakins, Julia; Hutton, Craig A.
Tetrahedron Letters, 2013 , vol. 54, # 7 p. 618 - 620
反应条件
scandium tris(trifluoromethanesulfonate) in dichloromethane T=20°C; 24 h;
参考文献
Tirotta, Ilaria; Fifer, Nathan L.; Eakins, Julia; Hutton, Craig A.
Tetrahedron Letters, 2013 , vol. 54, # 7 p. 618 - 620
反应条件
boron trifluoride diethyl etherate in chloroform
参考文献
Sparks, Steven M.; Banker, Pierette; Bickett, David M.; Clancy, Daphne C.; Dickerson, Scott H.; Garrido, Dulce M.; Golden, Pamela L.; Peat, Andrew J.; Sheckler, Lauren R.; Tavares, Francis X.; Thomson, Stephen A.; Weiel, James E.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 3 p. 981 - 985
反应条件
copper(II) bis(trifluoromethanesulfonate) in dichloromethane
T=20°C; 24 h;
参考文献
Tirotta, Ilaria; Fifer, Nathan L.; Eakins, Julia; Hutton, Craig A.
Tetrahedron Letters, 2013 , vol. 54, # 7 p. 618 - 620
