2-氧代茚满-1-甲酸甲酯合成路线 （共 10 条）
反应条件
1: With sodium in benzene 2: With hydrogenchloride in water; benzene
参考文献
Prescient Neuropharma Inc.
Patent: US7034055 B1, 2006 ;
Location in patent: Page/Page column 25 ;
反应条件
dirhodium tetraacetate in dichloromethane
参考文献
Taber,D.F.; Ruckle,R.E.
Journal of the American Chemical Society, 1986 , vol. 108, p. 7686
反应条件
poly(dimethylsiloxane-co-methylhydrosiloxane)trimethylsilyl terminated supported 1-carboxy-6-ethyl-1,8-diazabicyclo[5.4.0]undec-7-ene in methanol T=25 - 27°C; P=760.051 Torr; 4 h;
参考文献
Beckman, Eric J.; Munshi, Pradip
Green Chemistry, 2011 , vol. 13, # 2 p. 376 - 383
反应条件
1: 85 percent / methanesulfonyl azide, triethylamine / acetonitrile / 3 h / Ambient temperature 2: 76 percent / Rh2(OAc)4 / CH2Cl2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 108, p. 7686
反应条件
1: 85 percent / diisopropyl amine, n-BuLi / tetrahydrofuran / 1.) -78 deg C, 2.) r.t. 2: 85 percent / methanesulfonyl azide, triethylamine / acetonitrile / 3 h / Ambient temperature 3: 76 percent / Rh2(OAc)4 / CH2Cl2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 108, p. 7686
反应条件
sodium hydride in toluene T=25°C; Inert atmosphere;
参考文献
Diaf, Ilhem; Lemiere, Gilles; Dunach, Elisabet
Angewandte Chemie - International Edition, 2014 , vol. 53, # 16 p. 4177 - 4180
Angew. Chem., 2014 , vol. 126, # 16 p. 4261 - 4264,4
反应条件
1: 97 percent / p-toluenesulfonic acid / 6 h / Heating 2: 58 percent / sodium / toluene / 12 h / Heating View Scheme
参考文献
Chemistry Letters, , vol. 36, # 3 p. 420 - 421
反应条件
1: 68 percent / H2O / 48 h / 30 - 35 °C / baker's yeast 2: 57 percent / 1 M aq.NaOH / 1 h / Ambient temperature 3: 29 percent / diphenylphosphoryl azide (DPPA), Et3N / Heating 4: 80.6 percent / SOCl2 / Ambient temperature 5: 82.5 percent / aq.KOH / ethanol / 24 h / Heating View Scheme
参考文献
Didier, Eric; Loubinoux, Bernard; Ramos Tombo, Gerardo H.; Rihs, Grety
Tetrahedron, 1991 , vol. 47, # 27 p. 4941 - 4958
反应条件
1: 68 percent / H2O / 48 h / 30 - 35 °C / baker's yeast 2: 57 percent / 1 M aq.NaOH / 1 h / Ambient temperature 3: 29 percent / diphenylphosphoryl azide (DPPA), Et3N / Heating 4: 80.6 percent / SOCl2 / Ambient temperature 5: 82.5 percent / aq.KOH / ethanol / 24 h / Heating View Scheme
参考文献
Didier, Eric; Loubinoux, Bernard; Ramos Tombo, Gerardo H.; Rihs, Grety
Tetrahedron, 1991 , vol. 47, # 27 p. 4941 - 4958
反应条件
1: 68 percent / H2O / 48 h / 30 - 35 °C / baker's yeast 2: 57 percent / 1 M aq.NaOH / 1 h / Ambient temperature 3: 29 percent / diphenylphosphoryl azide (DPPA), Et3N / Heating 4: 80.6 percent / SOCl2 / Ambient temperature 5: 82.5 percent / aq.KOH / ethanol / 24 h / Heating View Scheme
参考文献
Didier, Eric; Loubinoux, Bernard; Ramos Tombo, Gerardo H.; Rihs, Grety
Tetrahedron, 1991 , vol. 47, # 27 p. 4941 - 4958
