hydrogenchloride in water; 1,2-dichloro-ethane T=20 - 60°C; 3 h;

1: (3S)-3-Hydroxypyrrolidine hydrochloride With sodium hydroxide in tetrahydrofuran 0.333333 h; 2: formaldehyd With formic acid in tetrahydrofuran; water T=60°C; 2 h; Reflux; 3: With sodium hydroxide in tetrahydrofuran; water T=0°C; pH=Ca. 10;

sodium bis(2-methoxyethoxy)aluminium dihydride in tetrahydrofuran; toluene 1 h; Heating;