2-氨基-3-溴苯甲酸甲酯合成路线 （共 13 条）
反应条件
1: With sulfuric acid 31 h; Reflux; 2: With sodium hydrogencarbonate in water
参考文献
WO2011/25859 A1, ;
Page/Page column 59 ;
WO 2011/025859 A1
反应条件
in tetrahydrofuran T=0 - 20°C; 0.5 h;
参考文献
US2008/153802 A1, ;
Page/Page column 114 ;
反应条件
dihydrogen peroxide in methanol T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1270 - 1274
反应条件
dihydrogen peroxide; sodium methylate in methanol; water Ambient temperature;
参考文献
Helvetica Chimica Acta, , vol. 71, p. 897 - 930
反应条件
sodium perborate; ammonium heptamolybdate; potassium bromide in acetic acid T=20°C; Bromination; 1.3 h;
参考文献
Tetrahedron Letters, , vol. 41, # 13 p. 2083 - 2085
反应条件
1: 1.) NH2OH*HCl; 2.) 90percent H2SO4 / 1.) H2O, 37-70 deg C, 60 h; 2.) 60 deg C 2: 60 percent / NaOMe, H2O2 / methanol; H2O / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 71, p. 897 - 930
反应条件
ammonium heptamolybdate; dihydrogen peroxide; potassium bromide in acetic acid T=20°C; Bromination; 0.5 h;
参考文献
Tetrahedron Letters, , vol. 41, # 13 p. 2083 - 2085
反应条件
1.1: sulfuric acid / 1 h / 60 - 80 °C 2.1: sodium hydroxide; water; dihydrogen peroxide / 0.5 h / 50 °C 2.2: pH 4 3.1: tetrahydrofuran / 0.5 h / 0 - 20 °C View Scheme
反应条件
1: thionyl chloride / 4 h / |Reflux 2: 0 °C View Scheme
参考文献
Molecules, , vol. 18, # 4 p. 4487 - 4509
参考文献
Molecules, , vol. 18, # 4 p. 4487 - 4509
