9-氨基-3,4-二氢吖啶-1(2H)-酮合成路线 (共 7 条)
反应条件
potassium carbonate; copper(l) chloride in tetrahydrofuran 5 h; Heating;
参考文献
Shutske; Pierrat; Kapples; Cornfeldt; Szewczak; Huger; Bores; Haroutunian; Davis
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1805 - 1813
反应条件
copper(l) chloride in tetrahydrofuran
参考文献
Hoechst-Roussel Pharmaceuticals Inc.
Patent: US4695573 A1, 1987 ;
反应条件
1: 68 percent / PTSA / toluene / Heating 2: 60 percent / K2CO3, CuCl / tetrahydrofuran / 18 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 5 p. 601 - 605
反应条件
1: 91.9 percent / p-toluenesulfonic acid monohydrate / toluene / 2 h / Heating 2: 62.3 percent / K2CO3 / CuCl / tetrahydrofuran / 5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 8 p. 1805 - 1813
反应条件
sulfuric acid-modified polyethylene glycol 6000 T=130°C; Friedlaender synthesis; 0.15 h; Microwave irradiationNeat (no solvent);
参考文献
Hasaninejad, Alireza; Zare, Abdolkarim; Shekouhy, Mohsen; Ameri-Rad, Javad
Green Chemistry, 2011 , vol. 13, # 4 p. 958 - 964
反应条件
oct-1-ene; palladium on activated charcoal 16 h; Heating;
参考文献
Shutske, Gregory M.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1617 - 1621
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane; water 4 h;
参考文献
Shutske; Pierrat; Kapples; Cornfeldt; Szewczak; Huger; Bores; Haroutunian; Davis
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1805 - 1813