1,3-二甲基-1H-吡唑-4-硼酸频哪醇酯合成路线 (共 3 条)
反应条件
1: 4-bromo-1,3-dimethyl-1H-pyrazole With tert.-butyl lithium in diethyl ether T=-78°C; 0.583333 h; Inert atmosphere; 2: 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in diethyl ether T=-78 - 25°C; 0.75 h; Inert atmosphere;
参考文献
WO2013/91096 A1, ;
Page/Page column 47 ;
反应条件
n-butyllithium in tetrahydrofuran T=-78 - 20°C; 1.08333 h;
参考文献
US2013/123281 A1, ;
Paragraph 0127; 0128 ;
反应条件
potassium carbonate in acetonitrile T=20°C;
参考文献
WO2010/51373 A1, ;
Page/Page column 74 ;
WO 2010/051373 A1