1-苄氧羰基-4-乙胺基哌啶合成路线 （共 4 条）
反应条件
1: With 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; potassium iodide in ethanol T=20°C; 113 h; 2: With hydrogenchloride in ethanol T=20°C; 36 h;
参考文献
Nieto, Rosa Maria; Coelho, Alberto; Martinez, Ana; Stefanachi, Angela; Sotelo, Eddy; Ravina, Enrique
Chemical and pharmaceutical bulletin, 2003 , vol. 51, # 9 p. 1025 - 1028
反应条件
benzaldehyde; N-ethyl-N,N-diisopropylamine; sodium chloride in toluene
反应条件
1.1: 90 percent / K2CO3 / acetonitrile / 96 h / 20 °C 2.1: hexamethylenetetramine; KI / ethanol / 113 h / 20 °C 2.2: 73 percent / aq. HCl / ethanol / 36 h / 20 °C View Scheme
参考文献
Chemical and pharmaceutical bulletin, , vol. 51, # 9 p. 1025 - 1028
反应条件
benzaldehyde 1.) toluene, reflux, 3 h, 2.) toluene, 25 deg C, 3 d; Yield given. Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 1 p. 121 - 131
