1: 100 percent / CH2Cl2; diethyl ether / 1.) -20 deg C, 2 h, 2.) RT, 12 h 2: 88 percent / CH2Cl2 / 3 h / Irradiation 3: 55 percent / H2 / 5percent Pd/C / methanol; acetic acid / 3 h / 760 Torr / Ambient temperature View Scheme

Multi-step reaction with 2 steps 1: 84 percent / Et3N / dimethylformamide / 2 h / 90 °C2: 98 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene (DBU) / tetrahydrofuran / 0.5 h / 0 °C