3-[3-(三氟甲基)苯基]-1-丙胺合成路线 （共 5 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 4 h; Heating;
参考文献
Wang, Xin; Chen, Ying; Crockett, Richard; Briones, Jorge; Yan, Tony; Orihuela, Carlos; Zhi, Benxin; Ng, John
Tetrahedron Letters, 2004 , vol. 45, # 45 p. 8355 - 8358
反应条件
1: 92 percent / NH4OH / dioxane / 0 °C 2: 89 percent / H2 / Pd/C / methanol / 16 h / 20 °C 3: 65 percent / LAH / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 45, # 45 p. 8355 - 8358
反应条件
1: 89 percent / H2 / Pd/C / methanol / 16 h / 20 °C 2: 65 percent / LAH / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 45, # 45 p. 8355 - 8358
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 5 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 5, # 8 p. 1675 - 1683
反应条件
1: SOCl2, DMF / CHCl3 / 3.5 h / Heating 2: aq. NH3 / diethyl ether / 18.5 h 3: LiAlH4 / tetrahydrofuran / 5 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 5, # 8 p. 1675 - 1683
