5-乙酰基异噁唑-3-羧酸乙酯合成路线 （共 6 条）
反应条件
chromium(VI) oxide; acetic acid in water Ambient temperature;
参考文献
Chiarino; Grancini; Frigeni; Biasini; Carenzi
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 600 - 605
反应条件
1: 83 percent / acetic acid, bromine / CHCl3 / 48 - 50 °C 2: 87 percent / ethanol / 1.5 h / Heating View Scheme
参考文献
Chiarino; Grancini; Frigeni; Biasini; Carenzi
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 600 - 605
反应条件
sodium hydroxide in ethanol Ambient temperature;
参考文献
Lepage; Tombret; Cuvier; Marivain; Gillardin
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 6 p. 581 - 593
反应条件
1: 77 percent / 10percent aq. NaOH / ethanol / Ambient temperature 2: 60 percent / Et3N / tetrahydrofuran / 18 h / Ambient temperature View Scheme
参考文献
Lepage; Tombret; Cuvier; Marivain; Gillardin
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 6 p. 581 - 593
反应条件
bromine; acetic acid in chloroform T=48 - 50°C;
参考文献
Chiarino; Grancini; Frigeni; Biasini; Carenzi
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 600 - 605
反应条件
bromine; acetic acid in tetrachloromethane T=48°C; 0.166667 h;
参考文献
De Amici; Conti; Dallanoce; Kassi; Castellano; Stefancich; De Micheli
Medicinal Chemistry Research, 2000 , vol. 10, # 2 p. 69 - 80
