乙基5-(2-溴乙炔)异唑-3-羧酸酯合成路线 （共 5 条）
反应条件
bromine; acetic acid in chloroform T=48 - 50°C;
参考文献
Chiarino; Grancini; Frigeni; Biasini; Carenzi
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 600 - 605
反应条件
bromine; acetic acid in tetrachloromethane T=48°C; 0.166667 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, p. 337 - 342
反应条件
1: pyridinium chlorochromate; sodium acetate / CH2Cl2 / 20 °C 2: phenyltrimethylammonium tribromide / tetrahydrofuran / 25 °C View Scheme
参考文献
Medicinal Chemistry Research, , vol. 10, # 2 p. 69 - 80
反应条件
potassium hydrogencarbonate; thiourea in ethanol
参考文献
Zambon S.p.A.
Patent: US4766137 A1, 1988 ;
反应条件
in ethanol 1.5 h; Heating;
参考文献
Chiarino; Grancini; Frigeni; Biasini; Carenzi
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 600 - 605
