1-异丙基-1H-吲哚-2,3-二酮合成路线 （共 8 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C; 72 h;
参考文献
Josyula, Vara Prasad Venkata Nagendra; Luehr, Gary; Gordeev, Mikhail
Patent: US2006/229348 A1, 2006 ;
Location in patent: Page/Page column 11 ;
反应条件
CaH2
1) DMF, 40-50 deg C, 15-30 min, 2) DMF, 24 h; Yield given. Multistep reaction;
参考文献
Garden, Simon J.; Torres, Jose C.; Da Silva, Leonardo E.; Pinto, Angelo C.
Synthetic Communications, 1998 , vol. 28, # 9 p. 1679 - 1689
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C; 72 h;
参考文献
Luehr, Gary W.; Jain, Rama; Renslo, Adam; Josyula, Vara Prasad Venkata Nagendra; Gordeev, Mikhail F.
Patent: US2006/30609 A1, 2006 ;
Location in patent: Page/Page column 13 ;
反应条件
pyridinium chlorochromate in 1,2-dichloro-ethane
T=80°C; 2.5 h;
参考文献
Kumar, Chebolu Naga Sesha Sai Pavan; Devi, Chebrolu Lavanya; Rao, Vaidya Jayathirtha; Palaniappan, Srinivasan
Synlett, 2008 , # 13 p. 2023 - 2027
反应条件
copper(l) iodide; dimethyl sulfoxide
T=20 - 100°C; 12 h; Reagent/catalyst;
参考文献
Gui, Qingwen; Dai, Fenglin; Liu, Jidan; Chen, Peixing; Yang, Zhiyong; Chen, Xiang; Tan, Ze
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 21 p. 3349 - 3353
反应条件
[3H]-Nicotinic acid; tert.-butylhydroperoxide; copper diacetate in decane; toluene
T=100°C; 24 h; Schlenk technique;
参考文献
Liu, Tao; Yang, Haijun; Jiang, Yuyang; Fu, Hua
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 6 p. 1169 - 1176
反应条件
1: With sodium hydride in tetrahydrofuran; hexane; N,N-dimethyl-formamide
T=0°C; 0.5 h;
2: in tetrahydrofuran; hexane; N,N-dimethyl-formamide
T=0 - 20°C;
参考文献
Shi, Feng; Tao, Zhong-Lin; Luo, Shi-Wei; Tu, Shu-Jiang; Gong, Liu-Zhu
Chemistry - A European Journal, 2012 , vol. 18, # 22 p. 6885 - 6894
反应条件
hydrazine
T=130°C; 1.5 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2007/91147 A1, 2007 ;
Location in patent: Page/Page column 17 ;
