4-氯-3-羟基丁酸甲酯合成路线 （共 19 条）
反应条件
1: With sodium tetrahydroborate in methanol T=0 - 20°C; 2.25 h; 2: With hydrogenchloride; water in methanol
参考文献
Schrittwieser, Joerg H.; Lavandera, Ivan; Seisser, Birgit; Mautner, Barbara; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2293 - 2298
反应条件
dicobalt octacarbonyl T=20°C; P=760.051 Torr; 24 h;
参考文献
Denmark, Scott E.; Ahmad, Moballigh
Journal of Organic Chemistry, 2007 , vol. 72, # 25 p. 9630 - 9634
反应条件
(i) HCl, Et2O, (ii) (hydrolysis); Multistep reaction;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 72, p. 166 - 177
反应条件
sodium hydroxide; Enterobacter sp.DS-S-75 T=30°C; pH=6.7; 40 h; Enzymatic reaction; Product distribution; Further Variations:Reagents;
参考文献
Advanced Synthesis and Catalysis, , vol. 345, # 4 p. 437 - 455
反应条件
halohydrin dehalogenase Trp249Phe mutant; Tris-SO4 buffer T=22°C; pH=7.5; 5 h;
参考文献
Elenkov, Maja Majeric; Tang, Lixia; Hauer, Bernhard; Janssen, Dick B.
Organic Letters, 2006 , vol. 8, # 19 p. 4227 - 4229
反应条件
halohydrin dehalogenase Trp249Phe mutant; Tris-SO4 buffer T=22°C; pH=7.5; 5 h;
参考文献
Elenkov, Maja Majeric; Tang, Lixia; Hauer, Bernhard; Janssen, Dick B.
Organic Letters, 2006 , vol. 8, # 19 p. 4227 - 4229
反应条件
sodium hydroxide; Enterobacter sp.DS-S-75 T=30°C; pH=6.7; 40 h; Enzymatic reaction; Product distribution; Further Variations:Reagents;
参考文献
Advanced Synthesis and Catalysis, , vol. 345, # 4 p. 437 - 455
参考文献
Suzuki, Toshio; Idogaki, Hideaki; Kasai, Naoya
Tetrahedron Asymmetry, 1996 , vol. 7, # 11 p. 3109 - 3112
反应条件
sodium hydroxide; Enterobacter sp.DS-S-75 T=30°C; pH=6.7; 40 h; Enzymatic reaction; Product distribution; Further Variations:Reagents;
参考文献
Advanced Synthesis and Catalysis, , vol. 345, # 4 p. 437 - 455
反应条件
4-(N,N-dimethlyamino)pyridine
参考文献
Daiso Co., Ltd.
Patent: US5869694 A1, 1999 ;
