DL-4-氯-3-羟基丁酸乙酯合成路线 （共 23 条）
反应条件
formic acid; nicotinamide adenine dinucleotide; sodium formate; formate dehydrogenase in water T=30°C; pH=6.5; 3.5 h;
参考文献
Morikawa, Souichi; Nakai, Takahisa; Yasohara, Yoshihiko; Nanba, Hirokazu; Kizaki, Noriyuki; Hasegawa, Junzo
Bioscience, Biotechnology and Biochemistry, 2005 , vol. 69, # 3 p. 544 - 552
反应条件
D-glucose in N-dodecane; water T=30°C; pH=7; 24 h; aq. phosphate bufferMicrobiological reactionEnzymatic reaction; optical yield given as percent ee;
参考文献
Wu, Xiaodan; Han, Xiaoxiang; Zhou, Lingxiao; Li, Ang
Asian Journal of Chemistry, 2012 , vol. 24, # 11 p. 5151 - 5154
反应条件
4-amino-pyridine; dicobalt octacarbonyl T=30 - 35°C; P=7500.75 Torr; 28 - 30 h; Conversion of starting material;
参考文献
DAISO CO., LTD.
Patent: EP1616852 A1, 2006 ;
Location in patent: Page/Page column 4; 6 ;
反应条件
hydrogenchloride T=-20 - 25°C; 12 h;
参考文献
WO2005/115978 A1, ;
Page/Page column 9 ;
反应条件
sodium tetrahydroborate; L-(+)-tartaric acid in tetrahydrofuran T=0°C; 22 h; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Yatagai, Masanobu; Ohnuki, Takashi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 6 p. 1826 - 1828
参考文献
Jiang, Chengjun; Hong, Huabin
Letters in Organic Chemistry, 2012 , vol. 9, # 7 p. 520 - 521
反应条件
sodium tetrahydroborate; L-(+)-tartaric acid in tetrahydrofuran 120 h; Ambient temperature; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Yatagai, Masanobu; Ohnuki, Takashi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 6 p. 1826 - 1828
反应条件
dimethylsulfide; ozone
参考文献
Tetrahedron Asymmetry, , vol. 2, # 5 p. 343 - 346
参考文献
Tetrahedron Asymmetry, , vol. 7, # 11 p. 3109 - 3112
反应条件
NADPH-dependent 3-ketoacyl-(acyl-carrier-protein) reductase from Synechococcus sp. strain PCC 7942 T=30°C; pH=7; aq. phosphate bufferEnzymatic reaction; Kinetics; Concentration; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 69, # 3-4 p. 89 - 94
