4,6-二甲基-5,6-二氢-2(1H)-吡啶酮合成路线 （共 3 条）
反应条件
1: NH2OH*HCl; NaOAc / methanol; H2O / 2 h / Heating 2: pyridine / 1 h / 20 °C 3: HCl / methanol / 12 h / Heating View Scheme
参考文献
Kawanaka, Yasufumi; Kobayashi, Kaoru; Kusuda, Shinya; Tatsumi, Tadashi; Murota, Masanori; Nishiyama, Toshihiko; Hisaichi, Katsuya; Fujii, Atsuko; Hirai, Keisuke; Naka, Masao; Komeno, Masaharu; Nakai, Hisao; Toda, Masaaki
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 17 p. 2291 - 2294
反应条件
1: 67 percent / pyridine / CH2Cl2 / 2 h / Ambient temperature 2: 28 percent / 2.) sodium sulphite / 1.) CH2Cl2, 0 deg C -> r.t., 2.) H2O, CH2Cl2 View Scheme
参考文献
Bateson, John H.; Quinn, Alison M.; Smale, Terence C.; Southgate, Robert
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2219 - 2234
反应条件
sodium sulfite 1.) CH2Cl2, 0 deg C -> r.t., 2.) H2O, CH2Cl2; Yield given. Multistep reaction;
参考文献
Bateson, John H.; Quinn, Alison M.; Smale, Terence C.; Southgate, Robert
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2219 - 2234
